Description

Bacterial vaginosis is the most common cause of abnormal vaginal discharge among women of childbearing age and is associated with adverse birth outcomes. 

Clindamycin

Drug Class: Lincomycin antibiotics.

• A semisynthetic broad spectrum antibiotic effective in the treatment of most infections involving anaerobes and gram-positive cocci.
• 3-day regimen of clindamycin, given as intravaginal ovules, was as effective as and better tolerated than a 7-day regimen of oral metronidazole 500 mg, given twice daily, for treatment of bacterial vaginosis.

Clotrimazole

Drug Class: Imidazoles

• Effective and traditionally used antifungal agent having broad spectrum of antimycotic activity.
• 3-day clotrimazole therapy is an effective treatment for primary vaginal mycosis.
• An effective antimycotic agent which can be used for vulvovaginal candidasis during pregnancy without causing side effects.³
• A potent antifungal agent against Candida species as well as effective against Trichomonas vaginalis.
• Reduces vaginal burning, itching, and discharge in patient suffering from Bacterial vaginosis.

Tinidazole

Drug Class: Antiprotozoals.

• A nitroimidazole antitrichomonal agent effective against Trichomonas vaginalis, Entamoeba histolytica, and Giardia lamblia infections.
• A drug used against protozoan infections.
• Long half-life allows once a day regimens.
• Enhanced tolerance and reduced toxicity.
• Effective option in patients with refractory bacterial vaginosis or recurrent bacterial vaginosis.

COMBINATION:

• Fixed dose combination of Clindamycin, Clotrimazole & Tinidazole is effective & well tolerated in the treatment of mixed vaginosis due to bacterial, fungal & protozoal infection.

• The combination ensures a wider range of antimicrobial action with rapid & noteworthy symptomatic relief in patients with mixed vaginosis of bacterial, fungal & protozoal origin.

• Treatment with combination therapy provided prompt onset of relief.