STAGREL-A & A75 Tablets

Description

Clopidogrel 

• Drug class: Antiplatelet medications

• Clopidogrel is a prodrug, which needs to be metabolized in the liver into active metabolites.

• Clopidogrel efficiently reduces ADP-induced platelet aggregation (a key phenomenon in atherosclerosis & CVD) and prolongs bleeding time and is a safe and efficacious antiplatelet drug

Aspirin 

• Drug Class: NSAIDs

• The most widely tested antiplatelet regimen was aspirin.The benefit of low-dose aspirin therapy for the secondary prevention of serious cardiovascular events is clear.

• Aspirin has long been the therapeutic foundation of the secondary prevention of CVD, to which contemporary drugs such as statins, and other antithrombotics have been added.

Combination:

• Aspirin and clopidogrel are antiplatelet agents that display good antithrombotic activity.Clopidogrel in combination with aspirin is the current “gold standard” for reducing cardiovascular events.
• Clopidogrel plus aspirin can reduce the relative risk of adverse cardiovascular events by 20%, compared with aspirin alone.