A single-pill combination with a promising clinical impact on hypertension

COMPOSITION – Telmisartan 40 mg + Amlodipine Besilate 5 mg 



  • This combination works by direct AT-1 receptor blockade and calcium ions inhibition across cell membranes.
  • Enlisted as one of the effective choices for the first-line treatment of hypertension.
  • Excellent combination regimen for those with co-morbidities like diabetes mellitus, heart strokes, heart failure, and kidney problems.
  • Low-dose combination therapy appears a better therapeutic approach than high-dose mono-monotherapy
  • SBP target achieved in 80% cases of group A-(high dose mono-therapy of Telmisartan 80 mg) and 90.323% cases of group C-(Telmisartan 40 mg and Amlodipine 5 mg). 
  • Trials suggest that Telmisartan & Amlodipine combination in hypertension have profound complementary action.
  • Replacement of valsartan by Telmisartan in Amlodipine-treated hypertensive patients shows a significant reduction in both mean systolic BP and diastolic BP.
  • 143.7/82.3 mmHg at baseline to 135.4/77.5 mmHg after the Telmisartan treatment.
  • Additional BP lowering can be achieved by switching to 5 mg Amlodipine plus 40 mg Telmisartan from 5 mg Amlodipine plus 8 mg candesartan. 


Telmisartan 40 mg + Amlodipine Besilate 5 mg


  1. Hypertension
  2. Heart Stroke
  3. Kidney Problems
  4. Heart Failure