Buffered pantoprazole tablet effectively increases the pH of gastric content above 5 which protects it from acid degradation.

Rabeprazole sodium

• Rabeprazole sodium is an antiulcer drug in the class of Acid- or proton-pump inhibitor that inhibits basal and stimulated gastric acid secretion.

• Successfully treats some atypical GERD manifestations, such as dysphagia associated with GERD, GERD-related asthma, and chest pain, and in the therapy of Barrett’s esophagus.

• Eradicates Helicobacter pylori to reduce the risk of Duodenal Ulcer Recurrence.

• Suppress gastric acid secretion by inhibiting the gastric H+, and K+ ATPase at the secretory surface of the gastric parietal cell.

• Rabeprazole sodium produces a dose-related sustained inhibition of both basal and peptone meal-stimulated gastric acid secretion.

• Unlike other PPIs, rabeprazole forms a partially reversible bond with the proton pump; works at a broader range of stomach pH and thus may work for longer than other PPIs.

Sodium Bicarbonate

• Sodium bicarbonate in the outer layer is dissolved to act as an antacid in the stomach.
• Sodium bicarbonate as buffer protects active rabeprazole from gastric acid.
• Neutralizes the acid and gives immediate symptomatic relief.
• Increases pH in the gastric environment and thus facilitates the absorption of Rabeprazole.