- It reduces the synaptic release of several neurotransmitters, by binding to alpha2-delta subunits, and thus, reduces neuronal excitability and seizures.
- Effective in reducing pain and improving sleep disturbances due to diabetic pain
- Effectively manages neuropathic pain through inhibition of serotonin and norepinephrine reuptake.
- Blocks voltage-dependent calcium channels thereby enhancin-pregabalin activity
Pregabalin 75mg + Nortriptlyline 10mg
- Neuropathic Pain associated with diabetic peripheral neuropathy
- Adjunctive therapy for adult patier with partial onset seizures Fibromyalgia.