OSART-25&50 Tablets

Description

Losartan is the first of a new class of drugs to be introduced for clinical use in hypertension. It is a nonpeptide angiotensin II (AII) receptor antagonist; an important antihypertensive agent.

Losartan was the first ARB approved for pediatric hypertension by the United States FDA in 2004 following the completion of the required clinical trials.

Losartan Potassium

• Drug class:  Angiotensin receptor blockers (ARBs)

• Losartan has wonderful clinical effectiveness in the treatment of essential hypertension
  and congestive heart failure.

• Has beneficial effects on albumin excretion rate, blood pressure, and renal hemodynamics providing renoprotection in diabetic patients with chronic nephropathy.

• According to a clinical study, in hypertensive children 6 to 16 years of age, once-daily therapy with losartan lowered BP in a dose-dependent manner.

• Losartan reduced proteinuria in hypertensive and normotensive children with chronic kidney disease by 35.9% and was superior to both placebo (normotensive cohort) and amlodipine (hypertensive cohort). Additionally, Losartan reduced Systolic BP & Diastolic BP in both cohorts and was superior to amlodipine.