NITRODAY 2.5 CR Capsules

Description

Nitroglycerin

• Class of medications: Vasodilators
• Nitroglycerin is the oldest and most commonly prescribed short-acting anti-anginal agent; It is been in clinical use since 1879.
• Nitroglycerin has been FDA approved since 2000; for the acute relief of an attack or acute prophylaxis of angina pectoris secondary to coronary artery disease.

Mechanism

• Exhibits an anti-inflammatory action in patients with peripheral vascular disease.
• Nitroglycerin induces vascular smooth muscle relaxation via mechanisms involving conversion to Nitric oxide (NO), activation of the enzyme guanylyl cyclase, and stimulation of guanosine 3′,5′-monophosphate (cGMP) production.
• Also dilates the arteries leading to the heart which helps to improve the oxygen supply to the heart.
• Corrects the imbalance between the flow of oxygen and blood to the heart.