NIMUSTAR-100 DT Tablets

A Functional Drug from Rising Generation for Fruitful Therapy

COMPOSITION – Nimesulide 100 mg

Description

Both cyclooxygenase COX-1 and COX-2 in our body produce prostaglandins that promote inflammation, pain, and fever.

  • However, only COX-1 produces prostaglandins that activate platelets and protect the stomach and intestinal lining.  The blockage of COX-1 in consequence causes the adverse effects of NSAIDs. 
  • When the COX-1 enzyme is blocked, inflammation is reduced, but the protection of the lining of the stomach also is lost; this may lead to stomach upset as well as ulceration.
  • And COX-2 is responsible for the most inflammatory symptoms, such as pain, edema, fever, and increase in vessel permeability. 

So the selective inhibitors of COX-2 would be much more safe drugs, compared with the classical NSAIDs in the treatment of inflammatory diseases.  

Nimesulide 

  • Drug class: Sulphonanilide
  • Not only inhibits more selectively the activity of COX-2 but also some other properties that increase its anti-inflammatory and analgesic function.
  • Belongs to the new generation of NSAIDs, unique as it contains sulphonanilide group. 
  • Nimesulide (unlike most other NSAIDs) in the recommended doses appears to be well tolerated in aspirin-sensitive asthmatic patients. 
  • An effective and well-tolerated alternative to other NSAIDs for short-term treatment of pain and inflammation of osteoarthritis and various other causes. Drugs.

DOSAGE

  • At the recommended dosage of 100 mg twice a day nimesulide is as effective an analgesic and anti-inflammatory agent as classical NSAIDs. 

Composition

Nimesulide 100 mg

Indications

  1. Pain associated with osteoarthritis, cancer, thrombophlebitis, oral surgery
  2. Dysmenorrhoea in adults
  3. Pain associated with general surgery
  4. Fever and inflammation accompanying respiratory tract infections,
  5. Otorhinolaryngologic diseases or ENT (Ear, Nose & Throat) diseases
  6. Traumatic injury in adults and children