IPOD-CV Dry-Syrup / IPOD-CV Tablet

Two Pro Performers Together Perform Perfection

  1. Cefpodoxime Proxetil IP 50 mg + Potassium Clavulanic acid 31.125 mg
  2. Cefpodoxime 200 mg + Clavulanate 125 mg
Category:

Description

  1. Cefpodoxime Proxetil IP 50 mg + Potassium Clavulanic acid 31.125 mg
  2. Cefpodoxime 200 mg + Clavulanate 125 mg

The pathogens causing Respiratory Tract Infections are susceptible to beta-lactam antibiotics that include penicillins and cephalosporins.

While first- and second-generation cephalosporins could only be administered by intravenous or intramuscular injection, the development of third generation cephalosporins that are broad-spectrum and can be administered orally has significantly increased their value in the management of RTIs.

Cefpodoxime

Drug class: Cephalosporin antibiotics

  • Cefpodoxime is a third-generation semisynthetic cephalosporin stable towards the most commonly found plasmid-mediated beta-lactamases.
  • It has a broad spectrum of antibacterial activity encompassing both Gram-negative and Gram-positive bacteria, rendering it a possible option for empirical use in a wide range of community acquired infections in both adult and paediatric patients.

Clavulanate

Drug class: Beta-lactamase inhibitors

  • Clavulanate potassium is structurally related to penicillin and possesses the ability to inactivate a wide variety of beta-lactamase enzymes, thereby preventing the inactivation of the combining antibiotics, such as amoxicillin and cefpodoxime.
  • Clavulanic acid alone does not exert any clinically effective antibacterial effect.

Combination – Cefpodoxime Plus Clavulanic Acid

  • The presence of clavulanate potassium in the cefpodoxime-clavulanic acid combination further extends the antibiotic spectrum of cefpodoxime to include many bacteria normally resistant to cefpodoxime alone.
  • The mean Minimal Inhibitory Concentration values of cefpodoxime plus clavulanic acid are significantly lower in comparison with that of amoxicillin plus clavulanic acid for S. aureus.

Composition

  1. Cefpodoxime Proxetil IP 50 mg + Potassium Clavulanic acid 31.125 mg
  2. Cefpodoxime 200 mg + Clavulanate 125 mg

Indications

  1. Gonorrhea
  2. Upper and lower respiratory tract infections
  3. Acute maxillary sinusitis
  4. Skin and soft tissue infections
  5. Otitis media
  6. Urinary tract infections