L-ornithine L-aspartate (LOLA) is a hepatoprotective, useful in the treatment of high ammonia levels or when a patient’s liver function is extremely poor.
Serves as a stimulus for hepatic glutamine synthesis which may be defective in acute and chronic liver disease.
LOLA infusion can be used as a treatment for clinical encephalopathy in patients with liver failure as it,
improves neuropsychiatric status and
decreases serum levels of ammonia with a low incidence of adverse effects (less than 5%).
Ensured safe and relatively rapid improvement and shorter hospital stay in cirrhotic patients with advanced hepatic encephalopathy.
Effective not only in reducing hyperammonemia and the severity of this disease but also improves the patient’s quality of life.