Drug Class: Peptides.
- Glutathione (GSH) is a tripeptide antioxidant, is essential for cellular homeostasis and plays a vital role in diverse cellular functions.
- Administering GSH initiates T-cells to inhibit the growth of Mycobacterium tuberculosis inside macrophages.
- Increases levels of Interleukin-2, Interleukin-12, and Interferon-gamma, cytokines, which are known to be crucial for the control of intracellular pathogens.
- It is required by the immune system for two important reasons:
- it protects host immune cells through its antioxidant mechanism and
- it provides the optimal functioning of lymphocytes and other cells of the immune system.
- It plays a role as a potent antioxidant in preventing cellular damage caused by ROS.
- Is involved in several other cellular events, such as synthesis of proteins and DNA, transport, enzyme activity, nutrient metabolism, cell protection and protein S-glutathionylation.
- It is essential for the regeneration of other antioxidants, like vitamin E and C.