Description

The intravenous (IV) administration route for Diclofenac Sodium is a very interesting therapeutic option for pain treatment, particularly in the peri- and postsurgical settings.

• Diclofenac Sodium (NSAIDs)

• A phenylacetic acid derivative non-selectively inhibits cyclooxygenases COX-1 and COX-2.

• Highly effective at therapeutic doses in the treatment of pain and physical disability in rheumatic diseases. 

• Diclofenac sodium administration improves analgesia and Patients’ Satisfaction Score (PSS) after conventional radiofrequency (CRF) denervation.

• Compared to a 7-day dosage, a 3-day diclofenac sodium therapy has similar efficacy and less cost for the treatment of pain after CRF (cooled radiofrequency) neurotomy.

• Single dose of diclofenac effectively decreased the intensity of postoperative pain after bimaxillary osteotomy (Jaw surgery for realignment).

• 75 mg/1 mL solution of Diclofenac sodium administered as a 5-s i.v. bolus (a large volume of fluid) was well tolerated; suggesting a superior analgesic effect.