Drotaverine hydrochloride is a highly potent spasmolytic agent.
Acts as an antispasmodic agent by inhibiting the phosphodiesterase IV enzyme, specific for smooth muscle spasms and pain, and used to reduce excessive labor pain.
Mefenamic acid
Mefenamic acid is an Aminobenzoate, a subclass of analgesic with Non-steroidal anti-inflammatory properties.
It acts by binding the prostaglandin synthetase receptors COX-1 and COX-2, inhibiting the action of prostaglandin synthetase.
COMBINATION:
Oral drotaverine with mefenamic acid is effective in women undergoing hysteroscopy and endometrial biopsy.