Description

• Mefenamic acid (NSAID, Analgesic, and Antipyretic drug)

• Known as a prostaglandin synthesis inhibitor and is used for reducing blood loss volume. Aka anthranilic acid is a weak organic acid.

• Reduces the severity of dysmenorrhea effectively with moderate menstrual pain reduction. 

• Mefenamic acid reduced blood loss in women with anovulatory dysfunctional uterine bleeding, fibroids, intrauterine devices, and von Willebrand disease. 

Paracetamol (Analgesics and Antipyretics)

• A popular analgesic and antipyretic drug that is used for the relief of fever, headaches, and other minor aches and pains. 

• With low peripheral adverse effects, possibly related to its weak activity as an inhibitor of peripheral cyclooxygenase (COX).

• Suggested as a good tool for treating brain inflammation without compromising peripheral prostaglandin synthesis. 

Dicyclomine hydrochloride (Anticholinergic and Antispasmodic)

• Showed a remarkable inhibitory action against several pathogenic bacteria. 
• Has a direct relaxing effect on smooth muscles. 

COMBINATION & TREATMENT

• The combined dosage form is used to treat a certain type of intestinal problem called irritable bowel syndrome. 

• Helps to reduce the symptoms of stomach and intestinal cramping. 

• Works by slowing the natural movements of the gut and by relaxing the muscles in the stomach and intestines. 

• Highly effective and used in the treatment of spasmodic dysmenorrhoea intestinal colic, biliary colic, and ureteric colic.