BIOSPAS-P SUSPENSION

Description

• Paracetamol (Analgesics and Antipyretics)

• Has only central action; decreases prostaglandin synthesis in the brain with weak anti-inflammatory effect.
• First-line therapy of choice in adults & children with fever and pain.

• It is the drug of choice in patients that cannot be treated with NSAIDs, that includes children under 12 years of age.

• Mefenamic acid (NSAID, Analgesic, and Antipyretic drug)

• A commonly used NSAID that is a cyclooxygenase-1 and 2 inhibitor with anti-inflammatory properties, exerts neuroprotective effects and improves cognitive impairment. 

• Mefenamic acid is registered for use from six months of age and may be an alternative nonsteroidal anti-inflammatory drug (NSAID) to ibuprofen in children with fever. 

COMBINATION

• Mefenamic acid and paracetamol combination has central and peripheral action with greater anti-inflammatory effects.

• Both the drugs are NSAIDs and act by inhibiting the COX enzyme responsible for generating Prostaglandins (PGE2). 

• More efficacious than and best alternative to paracetamol as antipyretic in the Paediatric age group for better & fast recovery from febrile illness.