Fastomyxin-B (Polymyxin B for Injection USP 500000 IU)

Fastomyxin-B is a potent antibiotic containing Polymyxin B, used to treat severe bacterial infections. It is available in a 500000 IU single-dose vial for intrathecal, intramuscular, and intravenous infusion. Fastomyxin-B is an injectable powder formulation for critical care against multidrug-resistant Gram-negative bacteria.

  • Composition: Polymyxin B 500000 IU
  • Form: Single-dose vial (powder for solution)
  • Use: Intrathecal, Intramuscular, or Intravenous infusion
  • Indication: Severe bacterial infections, including those caused by multidrug-resistant Gram-negative bacteria.

Description

Fastomyxin-B (Polymyxin B for Injection USP 500000 IU) is a powerful antibiotic used primarily for treating life-threatening infections caused by Gram-negative bacteria. It is effective against multidrug-resistant organisms and is administered as a solution for injection, which can be given intramuscularly (IM), intravenously (IV), or intrathecally.

Key Features:

  • Contains 500000 Units of Polymyxin B, an antibiotic belonging to the polymyxin class.
  • Effective in treating severe infections, including those caused by multidrug-resistant Gram-negative bacteria such as Pseudomonas aeruginosa, Acinetobacter spp., and Enterobacteriaceae.
  • Available as a single-dose vial of powder for reconstitution, providing flexibility in administration routes, including intrathecal, intramuscular, or intravenous infusion.

Indications: Fastomyxin-B is indicated for treating severe infections, including but not limited to:

  • Bacteremia
  • Meningitis
  • Urinary Tract Infections (UTIs)
  • Intra-abdominal infections
  • Skin and soft tissue infections

Administration:

  • To be reconstituted and administered either intramuscularly, intravenously, or intrathecally under the guidance of a healthcare professional.

Precautions:

  • Use cautiously in patients with renal impairment.
  • Avoid use in individuals allergic to polymyxin B or any of its components.

Storage Instructions:

  • Store in a dry place below 25°C, protected from light and moisture.
  • Once reconstituted, use immediately or store according to the prescribed conditions.